Just atmospheric pressure, really.
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Wait a minute, somethings DEFINITELY wrong with that airfare, just priced it out directly from American Airlines and its only $2k round trip from nearest airport to final destination...
Once a year, my wife brings up doing a mission thing for the hospital she works at. They cover in country expenses and pay her salary, but we'd have to foot the travel bill and I'd be mostly fawked for work unless I had good intarwebz and had some remote projects.
South America, African continent mostly from what I understand. IIRC, it's a 3-6 month gig.