I tried the Truglos a few years back on a pistol. I found them to be lacking in both speed and accuracy for me. I put more emphasis on accuracy but I want speed too.
I should note that when I talk about speed and accuracy I'm talking about quantifiable things and sometimes the differences are minute.
If I can run .25 sec splits with one set of sights and .20 sec splits with another set (while not losing anything in accuracy), I'm going to go with the second set. The .05 seconds might not actually matter much in real life, but I'm going to try an stack the deck in my favor as often as I can.