What erni said. It's completely possible. Get subs lined up for any work you're not going to do yourself. Warn your day job. Have a pickup truck.

Consider blueprints that spec any unnecessary rooms as unfinished and diy later. I knew a guy that would only finish the master suite and the kitchen blueprints for a 6 bedroom house and build out on a remodel permit later.

Consider dropping any outbuildings first to stage materials and tools in if you're going to be doing the work yourself.

There's a reason gc's make 10% it's a pain in the ass and if you're not doing at least one subs job or the partial build as above I would advise against it.