Just chiming back in here since I have some recent experience, as in yesterday.

My teammate and I finished our last training ruck before the SAC (Sniper Adventure Challenge) 11 days from today. We did 33 miles with 3,800 feet of elevation. 40# in the bag.

I wore my favorite trail runners (Altra Timp 1.5), Injiji toe sock liners, and Darn Tough mid-weight hiking socks.

I came home with a trivial blister on the tip of two toes, the first ones in from the big toe. They were downhill blisters from a long and miserable descent. I forgot to tighten up my laces and my feet were sliding too far forward. Dumbass!

If you can do without the ankle support hiking boot, trail runners make you fast, light, and the nimble.