I used a Hill People Gear when I would run, had a .38 or a Glock 43 in there and could carry my phone/keys/etc. I went with the runners model, more slick than MOLLE.
Not the fastest draw, but was super comfortable to run with.
I guess it comes down to option to conceal or not. If you're hunting no one is going to look twice at you with a revolver strapped on your chest. If you're hiking/etc., I'd go with the Hill People.