I'm cooling my whole house with a swamp cooler mounted in a window. It really helps with humidity, especially when it is single digit humidity outside. Average humidity is 47% inside. When the temp is triple digits, I end up running the central air conditioning too. Denver is usually 15-20 degrees cooler than Pueblo in summer.
I remove the swamp cooler in the winter. Biggest pain in the ass is setting back in the window the next summer. It has to be cleaned of mud (dust) and scale before reinstall in the window.

I don't notice any problem with moisture in the house. If anything, the air is too dry here.