We clean our mirrors with a CO2 "snow" (liquid CO2 which is passed through a nozzle and expanded rapidly to sublimate into a snowlike form that evaporates after about 18" once it leaves the tube), which knocks a majority of the dust off. The drive surfaces are cleaned/lubricated usually the same time. During the dusty/pollen seasons, they clean those every other day if its bad. When its not the dusty season, they try to clean once every other week. We realuminize our mirror every other year, or strip it down to the glass, then re-apply a 40-60 micron thick layer of aluminum that is the mirror's reflective surface.
Because we are a survey telescope, we clean more regularly than most telescopes, because we want the data throughout the 4-6 year surveys to be taken with nearly identical conditions, meaning a mirror between 0-2 dirty, instead of first year getting that and the dirtiness slowly increasing towards the end of the survey. And that is an arbitrary number.