I haven't hunted with an Ar-10 type weapon, but I have been next to a guy who did. It came down to weight. We were up in Montana in some deep snow, with a fair bit of gear and he sold his rifle shortly after we got back. It was just too heavy to be in love with and the firepower doesn't mean much hunting. We were after Coyotes and I had a regular AR with an ACOG on top, much happier with it.

I lean on getting two guns. 308 ammo isn't cheap, and it kicks a good bit. As to a hunting guy, you can get into a light rifle that shoots a very flexible and powerful round for ~$400 if you are just aiming for hunting without any serious trouble, and then keep your AR as is or make it how you want it. dollar for dollar, any AR10 worth its salt will cost you more if you watch your pennies with the two.

I tried real hard to pull off the "one gun" thing, and there isn't really a platform that is fun/cheap at a range AND easy to pack and hunt with AND able to take CONUS sized game AND able to put by the bed side and feel safe. Maybe a SCAR 17 or an M1a, maybe, but they can both pack on the pounds. I even tried a Ruger Scout, did it all, just not a ton of fun at a range.