I have one hunting load for anything from Antelope to Elk - using 165 grain Sierra GameKing hollowpoints in a .308, at about 2550 fps at the muzzle. I've used it for a nice cow elk at 325 yards, an antelope at 520 yards, and so on. It isn't the latest, or greatest, or fancy, but if I put it in the right place it has worked every time for me.