Yep. My wife, who has her license as well, routinely talks to me, as I drive home from work at night. She uses the radio at home, or her hand held, and I use the radio in the jeep. All one has to do is dial in to the same repeater on both radios, or if close enough or where terrain permits, the same frequency for direct(simplex) communications. If colorado connections or colorado repeater association has their uplink working, I could turn it on right now and hit you on the radio.